Top 10 Knee Injection Clinics in USA
Knee Injections Near You in USA
Top 10 Knee Injection Clinics in USA
Knee pain is a growing concern for millions of Americans. Whether caused by arthritis, injury, or general wear and tear, knee discomfort can severely limit your ability to live an active life. Fortunately, a knee injection can be a highly effective, non-surgical solution to relieve pain, reduce inflammation, and improve joint function.
If you're looking for the most reputable clinics offering knee injection therapy, this guide will walk you through the top 10 across the USA. These clinics are known for exceptional care, modern technology, and proven results—starting with the renowned Menz Clinic.
1. Menz Clinic – Orlando, Florida
At the forefront of knee injection therapy in the United States is Menz Clinic, based in Orlando, FL. With a reputation for excellence in pain management and regenerative medicine, Menz Clinic is the go-to destination for patients seeking lasting relief without surgery.
Why Menz Clinic Leads the List:
Specialized in PRP (Platelet-Rich Plasma) and hyaluronic acid knee injections
State-of-the-art technology and a compassionate team of specialists
Tailored treatment plans for arthritis, joint degeneration, and sports injuries
Trusted by both everyday individuals and professional athletes
Menz Clinic stands out for delivering results that prioritize patient comfort, long-term relief, and enhanced mobility.
📍 Location: Orlando, FL
🌐 Website: menzclinic.com
2. Cleveland Clinic – Cleveland, Ohio
Cleveland Clinic offers comprehensive orthopedic care, including cutting-edge knee injection treatments designed to minimize pain and restore joint function.
Highlights:
Use of image-guided injections for maximum precision
Options include corticosteroid and hyaluronic acid knee injections
Strong focus on research-based pain management
With a multidisciplinary approach, Cleveland Clinic ensures patients receive thorough evaluations and the most effective treatments available.
3. Hospital for Special Surgery (HSS) – New York, New York
Known globally for its orthopedic expertise, HSS provides leading knee injection therapies that are often integrated with physical therapy for holistic recovery.
Services Offered:
Steroid, gel, and regenerative knee injections
Advanced diagnostics to determine the best treatment path
Collaborative care model between orthopedists and physical therapists
Patients travel from across the country for HSS’s elite-level knee care.
4. Mayo Clinic – Rochester, Minnesota
Mayo Clinic delivers world-class care in every medical specialty, and their orthopedics team is no exception. Their customized knee injection treatments provide significant relief for a wide range of conditions.
Notable Offerings:
Hyaluronic acid knee injections for smoother joint motion
Cortisone shots for reducing severe inflammation
PRP and regenerative options for long-term healing
Mayo Clinic is a top choice for patients looking for trusted, evidence-based treatment.
5. Rush University Medical Center – Chicago, Illinois
Rush University’s orthopedics department combines innovation with compassionate care. Their knee injection services are ideal for individuals seeking fast, non-invasive relief.
Why Patients Choose Rush:
Expertise in ultrasound-guided knee injections
Offers both short-term and long-term pain relief options
Emphasis on functional rehabilitation post-treatment
Rush is a pioneer in both research and patient satisfaction.
6. Johns Hopkins Orthopaedics – Baltimore, Maryland
Johns Hopkins provides patients with a blend of advanced technology and clinical experience. Their team specializes in knee injection therapy for chronic pain, injury recovery, and arthritis management.
Available Treatments:
Cortisone, PRP, and viscosupplementation knee injections
Imaging tools to guide injection placement
Care customized to each individual’s lifestyle and condition
As one of the nation's most respected institutions, Johns Hopkins ensures high-quality, results-driven care.
7. Kerlan-Jobe Institute – Los Angeles, California
Located in the heart of Southern California, Kerlan-Jobe is a leader in sports medicine and orthopedics. Their knee injection treatments are widely used by elite athletes and weekend warriors alike.
Services Include:
PRP and stem cell knee injections to promote healing
Same-day appointments for acute injuries
Extensive experience with professional sports teams
If performance and rapid recovery are priorities, Kerlan-Jobe is a trusted option.
8. OrthoCarolina – Charlotte, North Carolina
OrthoCarolina is one of the largest orthopedic practices in the Southeast, offering extensive knee injection services at multiple convenient locations.
Benefits of Choosing OrthoCarolina:
Wide range of injection options including corticosteroids and hyaluronic acid
Same-day diagnostics and care plans
Supportive post-injection physical therapy programs
They focus on reducing downtime and helping patients get back to doing what they love.
9. Texas Orthopedics – Austin, Texas
Texas Orthopedics provides specialized knee injection care in a modern, patient-friendly environment. With board-certified orthopedic physicians on staff, patients receive tailored care for chronic and acute knee pain.
Top Services:
Cortisone knee injections for fast inflammation relief
Lubricating injections to ease joint friction
Regenerative injections available upon consultation
Their team is highly rated for both professionalism and results.
10. Andrews Sports Medicine – Birmingham, Alabama
Founded by Dr. James Andrews, this clinic is known for its excellence in sports-related injuries and advanced knee injection procedures.
What They Offer:
PRP, stem cell, and hyaluronic acid knee injections
Comprehensive evaluation and diagnostic imaging
Recovery plans that integrate rehab and follow-up care
Athletes from all over the U.S. rely on Andrews Sports Medicine for expert joint care.
Common Types of Knee Injections Offered
Understanding your options can help you make the best decision for your condition. Here's a breakdown of the most common types of knee injections:
Corticosteroid Injections – Offer quick relief for inflammation and swelling.
Hyaluronic Acid (Gel Injections) – Lubricates the joint to ease movement and reduce friction.
Platelet-Rich Plasma (PRP) – Stimulates tissue regeneration using your own blood platelets.
Stem Cell Therapy – A regenerative approach that may help repair joint cartilage over time.
Each top clinic on this list is equipped to provide one or more of these options based on your diagnosis.
Benefits of Knee Injection Therapy
Why choose a knee injection instead of surgery or long-term medications? Here are some key benefits:
Minimally Invasive: No surgery or downtime required
Quick Relief: Many patients feel improvement within days
Affordable: Often covered by insurance and more cost-effective than surgery
Repeatable: Injections can be administered multiple times a year
Customizable: Tailored to specific conditions like arthritis or injury
A knee injection is an excellent first step before considering more aggressive treatments like surgery.
When Should You Consider a Knee Injection?
You may be a candidate for a knee injection if:
You’ve been diagnosed with osteoarthritis, rheumatoid arthritis, or joint degeneration
Over-the-counter medications and physical therapy haven’t worked
You experience stiffness, swelling, or decreased range of motion
You want to avoid or delay surgery
Always consult with a qualified specialist to determine the right treatment for your needs.
Final Thoughts: Start Your Journey to Pain-Free Knees
Chronic knee pain doesn’t have to control your life. With the right knee injection therapy, you can get back to walking, running, and living without constant discomfort.
If you’re ready to take that step, start with the best, Menz Clinic in Orlando. Their advanced therapies, expert staff, and patient-first approach make them the top choice for knee injection treatment in the USA.
From coast to coast, each clinic in this list offers specialized care designed to help you live pain-free. Explore your options, book a consultation, and take control of your joint health today.